ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,564, issued on March 17, was assigned to Alnylam Pharmaceuticals Inc. (Cambridge, Mass.).
"Sterol regulatory element binding protein (SREBP) chaperone (SCAP) iRNA compositions and methods of use thereof" was invented by Kevin Fitzgerald (Brookline, Mass.), Huilei Xu (Boston) and Gregory Hinkle (Plymouth, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to double stranded ribonucleic acid (dsRNAi) agents and compositions targeting the SCAP gene, as well as methods of inhibiting expression of a SCAP gene and methods of treating subjects having a SCAP-associated disorder, such as nonalcoholic fatty liver disease (NAFLD) or no...