ALEXANDRIA, Va., July 21 -- United States Patent no. 12,685,763, issued on July 21, was assigned to Alexion Pharmaceuticals Inc. (Boston).

"Methods for treating intracranial hemorrhage and assessing efficacy" was invented by Patrick Yue (South San Francisco, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods useful for assessing the hemostatic efficacy in a patient having suffered from intracranial hemorrhage while undergoing an anticoagulation treatment with a factor Xa (fXa) inhibitor are described. The method can include administering to the patient a fXa derivative that has reduced catalytic activity as compared to the wild-type fXa protein, is capable of binding to the factor...