ALEXANDRIA, Va., March 17 -- United States Patent no. 12,576,141, issued on March 17, was assigned to AlbuNext LLC (El Segundo, Calif.).
"Albumin bound macromolecule tri-agonist activating GLP-1/GIP/glucagon receptors" was invented by Patrick Soon-Shiong (Culver City, Calif.), Martin Robitaille (Saint-Colomban, Canada) and Bing Song (El Segundo, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A pharmaceutical composition comprises a GPCR agonist fusion protein in which a GPCR agonist peptide is covalently coupled to albumin via a linker in a manner that is resistant to a retro-Michael addition. Advantageously, compositions presented herein avoid decoupling of the agonist form the albumin while retainin...