ALEXANDRIA, Va., July 16 -- United States Patent no. 12,667,087, issued on June 30, was assigned to Agios Pharmaceuticals Inc. (Cambridge, Mass.).

"Methods of treatment with aminolevulinic acid synthase 2 (ALAS2) modulators" was invented by Shengfang Jin (Newton, Mass.), Barden Chan (Brookline, Mass.) and Gavin Whissell (Belmont, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein is a compound of Formula I or a pharmaceutically acceptable salt thereof: wherein Ring A R1, R2, a, b, and n are as defined herein. Also described is a method of treating a subject having a disorder in need of treatment, comprising inhibiting aminolevulinic acid synthase 2 (ALAS2) in the subject by administering a...