US Patent Issued to Agios Pharmaceuticals on July 7 for "Compounds and methods useful for stabilizing phenylalanine hydroxylase mutations" (Massachusetts, New Jersey Inventors)

ALEXANDRIA, Va., July 7 -- United States Patent no. 12,673,961, issued on July 7, was assigned to Agios Pharmaceuticals Inc. (Cambridge, Mass.).

"Compounds and methods useful for stabilizing phenylalanine hydroxylase mutations" was invented by Lucrezia De Pascalis (Cambridge, Mass.), Heather Jane Finlay (Skillman, N.J.), Sandra King (Jamaica Plain, Mass.), Zenon D. Konteatis (Chatham Township, N.J.) and Brian C. Shook (Holliston, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to compounds of Formula I or a pharmaceutically acceptable salt thereof, wherein, m, R1-R5, R5A, and L are defined herein.These compounds are useful in methods for stabilizing a mutant PAH protein or reducin...