US Patent Issued to Agency for Science, Technology and Research on June 30 for "Methods for manipulating cell state transitions in cancer" (Singaporean Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,667,546, issued on June 30, was assigned to Agency for Science, Technology and Research (Singapore).

"Methods for manipulating cell state transitions in cancer" was invented by Wai Leong Tam (Singapore), Ser Yue Loo (Singapore) and Li Ping Toh (Singapore).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method of inducing mesenchymal-epithelial transition (MET) in a basal-like (or mesenchymal-like) cancer cell by contacting the cancer cell with an inducer of mesenchymal-epithelial transition for a time and under conditions sufficient to induce MET in the cell. Additionally, there is also provided a method of inhibiting ep...