ALEXANDRIA, Va., March 24 -- United States Patent no. 12,584,115, issued on March 24, was assigned to ADVANCED SOLUTIONS LIFE SCIENCES LLC (Louisville, Ky.).
"Models and methods to establish perfusable, compartmentalized, lymphoid tissue models in three-dimensional in vitro culture" was invented by James B. Hoying (Manchester, N.H.), Hannah A. Strobel (Manchester, N.H.) and Sarah Moss (Manchester, N.H.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A three-dimensional (3D) lymphoid tissue model is provided, the model including a cellularized stromal compartment and a plurality of cellularized compartments including lymphocytes disposed within the stromal compartment; and a controlled fluid perfusion system c...