US Patent Issued to Adagene on Nov. 3 for "Dynamic human antibody light chain libraries" (Chinese, American Inventors)

ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,781,391, issued on Nov. 3, was assigned to Adagene Inc. (Grand Cayman, Cayman Islands).

"Dynamic human antibody light chain libraries" was invented by Peter Peizhi Luo (Lansdale, Pa.), Yan Li (Suzhou, China) and Fangyong Du (Suzhou, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are libraries containing polynucleotides, where one of the polynucleotides encodes an antibody light chain with specific hypervariable regions HVR-L1, HVR-L2, and HVR-L3. Further provided herein are libraries containing polynucleotides encoding a plurality of unique antibodies, wherein each antibody comprises a heavy chain variable region and a light chain v...