ALEXANDRIA, Va., July 14 -- United States Patent no. 12,678,515, issued on July 14, was assigned to Acuitas Therapeutics Inc. (Vancouver, Canada).

"Lipids and lipid nanoparticle formulations for delivery of nucleic acids" was invented by Steven M. Ansell (Vancouver, Canada) and Xinyao Du (Richmond, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds are provided having the following structure (I) or (II): or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R, R1, R2, L, X, L, G1, G2, Z, a1, a2 and n are independently as defined herein for each of structures (I) and (II). Use of the compounds as a component of lipid nanoparticle formulations for delivery of a therapeut...