ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,714,670, issued on Aug. 25, was assigned to Acuitas Therapeutics Inc. (Vancouver, Canada).

"Carbonyl lipids and lipid nanoparticle formulations for delivery of nucleic acids" was invented by Xinyao Du (Richmond, Canada) and Steven M. Ansell (Vancouver, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds are provided having one of the following structures (I) or (II): or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R3a, R3b, L1, L2, G1a, G1b, G2a, G2b and G3 are as defined herein. Use of the compounds as a component of lipid nanoparticle formulations for delivery of a therapeutic agent, compositions comprising...