ALEXANDRIA, Va., Aug. 18 -- United States Patent no. 12,708,678, issued on Aug. 18, was assigned to Actinium Pharmaceuticals Inc. (New York).
"Stabilized radiolabeled anti-CD45 immunoglobulin compositions" was invented by Kaushik Dave (Edison, N.J.) and Shubh Sharma (Cranbury, N.J.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods are described for stabilizing a radio-iodinated monoclonal IgG antibody for up to 17 days against radiolytic decomposition. The stabilized radiolabeled murine antibody binding the CD45 antigen expressed on various forms of lymphomas is useful as a radiotherapeutic and diagnostic agent in the treatment of human malignancies of hematopoietic origin, including ly...