US Patent Issued to 3T BIOSCIENCES on March 24 for "T cell receptor (TCR) compositions and methods for optimizing antigen reactive T-cells" (California Inventors)

ALEXANDRIA, Va., March 24 -- United States Patent no. 12,584,107, issued on March 24, was assigned to 3T BIOSCIENCES INC. (South San Francisco, Calif.).

"T cell receptor (TCR) compositions and methods for optimizing antigen reactive T-cells" was invented by Leah Sibener (San Francisco), John Leonard (South San Francisco, Calif.), Alejandro Ramirez (South San Francisco, Calif.) and Marvin Gee (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are methods for isolating T-cells with T cell receptors (TCRs) optimized for reactivity to specific peptides and decreased cross-reactivity to non-target peptides. Advantageously, TCRs of the invention can be optimized to target cancer antigens and pe...