ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,791, issued on Feb. 24, was assigned to 10X GENOMICS INC. (Pleasanton, Calif.).
"Methods and compositions for in situ analysis of V(D)J sequences" was invented by Malte Kuhnemund (Stockholm).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates in some aspects to methods for analyzing antigen receptor transcripts in a biological sample. In some aspects, nucleic acid molecules are generated from V(D)J transcripts in situ in the biological sample to enrich molecules comprising V(D)J joins. In some aspects, the presence, amount, and/or identity of a plurality of V(D)J transcripts are analyzed in situ. Also provided are oligonucle...