ALEXANDRIA, Va., Sept. 1 -- United States Patent no. 12,721,884, issued on Sept. 1.
"Production of MHC II/CII complexes" was invented by Nadine Schneider (Frankfurt am Main, Germany), Bingze Xu (Uppsala, Sweden), Sylvia Cienciala (Nidderau, Germany), Rikard Holmdahl (Stockholm) and Harald Burkhardt (Frankfurt am Main, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to in situ glycosylated MHC II/CII peptide complexes, i.e., complexes naturally glycosylated during recombinant protein expression in the host cell. The invention further relates to methods of producing glycosylated MHC II/CII peptide complexes in mammalian cells. Furthermore the invention relates to the use of...