US Patent Issued on June 16 for "RNA preparations comprising purified modified RNA for reprogramming cells" (Pennsylvania, Wisconsin Inventors)

ALEXANDRIA, Va., June 16 -- United States Patent no. 12,655,395, issued on June 16.

"RNA preparations comprising purified modified RNA for reprogramming cells" was invented by Katalin Kariko (Rydal, Pa.), Drew Weissman (Wynnewood, Pa.), Gary Dahl (Madison, Wis.), Anthony Person (Madison, Wis.), Judith Meis (Fitchburg, Wis.) and Jerome Jendrisak (Madison, Wis.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides compositions and methods for reprogramming somatic cells using purified RNA preparations comprising single-strand mRNA encoding an iPS cell induction factor. The purified RNA preparations are preferably substantially free of RNA contaminant molecules that: i) would activate an...