US Patent Issued on July 14 for "Screening of fixed-point coupling sites of cysteine-modified antibody-toxin conjugate (TDC)" (Chinese Inventors)

ALEXANDRIA, Va., July 14 -- United States Patent no. 12,678,474, issued on July 14.

"Screening of fixed-point coupling sites of cysteine-modified antibody-toxin conjugate (TDC)" was invented by Yi Zhu (Chengdu, China), Yiqian Wang (Chengdu, China), Shi Zhuo (Chengdu, China), Jie Li (Chengdu, China), Yongguo Yu (Chengdu, China) and Weili Wan (Chengdu, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed in the present invention is a cysteine-modified antibody-toxin conjugate. The cysteine-modified antibody-toxin conjugate is characterized in that: the antibody is an antibody in which cysteine is inserted on a fixed point, and insertion sites of the cysteine comprising one or more of the following si...