ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,551,584, issued on Feb. 17.
"Lewis Y radioimmunotherapy for the treatment of cancer" was invented by Dale L Ludwig (Rockaway, N.J.) and Eileen Geoghegan (Mamaroneck, N.Y.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are compositions and methods for treating Lewis Y antigen positive cancers in mammalian subjects by administering an effective amount of a radionuclide-labeled Lewis Y antigen targeting agent such as an antibody labeled with an alpha particle-emitting radionuclide such as 225Ac. The methods may further include administration of additional agents, such as radiosensitizing agents, immune checkpoint therapies, CD47 blockades, and/or ...