BETHESDA, Md., Sept. 11 -- The U.S. Department of Health & Human Services' National Institutes of Health issued the following press release:
A scientific team funded by the National Institutes of Health (NIH) has developed a laboratory model that reveals how antibody-producing plasma cells migrate, mature, and survive within human bone marrow, a main location of long-lived antibody-producing plasma cells. The platform combines a lymph node mimicking organoid with a tissue chip that mimics bone marrow, allowing scientists to observe key stages of plasma cell development that have been difficult to study in humans. Analysis of the cells in the tissue chip provides essential new information that advances our understanding of plasma cell devel...