International Clinical Trial: Outcome of Targeted Therapy for Obstructive Sleep Apnea in Children with Obesity and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Geneva, Aug. 6 -- International Clinical Trials Registry received information related to the study (TCTR20260726008) titled 'Outcome of Targeted Therapy for Obstructive Sleep Apnea in Children with Obesity and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)' on July 26.

Study Type: Interventional

Study Design: Non-randomized

Primary Sponsor: Chonburi Hospital

Condition: Targeted treatment of pediatric OSA was associated with significant improvement in sleep-disordered breathing and biochemical markers of liver injury in children with obesity and MASLD. Clinically meaningful improvement in ALT was independently associated with CPAP therapy and better nocturnal oxygenation, supporting the hypothesis that correction of...