Geneva, March 23 -- International Clinical Trials Registry received information related to the study (ChiCTR2600120131) titled 'Effectiveness and Safety of Dexmedetomidine and Esketamine Combined Infusion on Difficult-to-Treat Depression with Comorbid Insomnia: A Multicenter, Prospective, observational Real-World Study' on March 10.

Study Type: Observational study

Study Design: Cohort study

Primary Sponsor: Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine

Condition: Treatment-resistant depression insomnia

Recruitment Status: Not Recruiting

Phase: N/A

Date of First Enrollment: 2026-04-01

Target Sample Size: Observation group:45;

Countries of Recruitment: China

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