International Clinical Trial: A Single-Arm,Multicenter Phase, Phase II Clinical Trial of Adebrelimab Combined With Trametinib in the Treatment of Refractory Recurrent Langerhans Cell Histiocytosis in Children and Adolescents

Geneva, Nov. 2 -- International Clinical Trials Registry received information related to the study (NCT07890701) titled 'A Single-Arm,Multicenter Phase, Phase II Clinical Trial of Adebrelimab Combined With Trametinib in the Treatment of Refractory Recurrent Langerhans Cell Histiocytosis in Children and Adolescents' on Oct. 16.

Study Type: Interventional

Study Design: Allocation: N/A. Intervention model: Single Group Assignment. Primary purpose: Treatment. Masking: None (Open Label).

Primary Sponsor: Second Affiliated Hospital of Wenzhou Medical University

Condition: Histiocytosis,Langerhans-Cell

Intervention: Drug: treated group

Recruitment Status: Recruiting

Phase: Phase 1/Phase 2

Date of First Enrollment: October 20, 2026 ...