International Clinical Trial: A multicenter, single-arm phase II clinical trial of low-dose radiotherapy combined with PD-1 monoclonal antibody as neoadjuvant immunotherapy for surgically resectable locally advanced head and neck squamous cell carcinoma (HNSCC)

Geneva, Sept. 21 -- International Clinical Trials Registry received information related to the study (ChiCTR2600132265) titled 'A multicenter, single-arm phase II clinical trial of low-dose radiotherapy combined with PD-1 monoclonal antibody as neoadjuvant immunotherapy for surgically resectable locally advanced head and neck squamous cell carcinoma (HNSCC)' on Sept. 11.

Study Type: Interventional study

Study Design: Single arm

Primary Sponsor: The Fifth Affiliated Hospital, Sun Yat-Sen University

Condition: Head and neck squamous cell carcinoma (oral cavity, oropharynx, hypopharynx, or larynx)

Recruitment Status: Recruiting

Phase: 2

Date of First Enrollment: 2026-02-10

Target Sample Size: Low-Dose RT plus Anti-PD-1 Imunother...