U.S., Oct. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07905378) titled 'Validation of Wearable Core Body Temperature-Based Circadian Rhythm Digital Biomarkers' on Oct. 11.
Brief Summary: This single-site prospective observational study aims to validate wearable-derived circadian and behavioral rhythm biomarkers using continuous core body temperature and raw accelerometry measurements and to explore longitudinal changes in circadian and rest-activity rhythms in psychiatric inpatients.
The study consists of two complementary substudies. Study 1 will enroll 150 outpatients and community participants, including 75 patients with major depressive disorder or bipolar I/II disorder and 75 healthy controls. Par...