Clinical Trial: Vaginal Prasterone Versus Estriol in Women With Pelvic Floor Disorders

U.S., Oct. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07854873) titled 'Vaginal Prasterone Versus Estriol in Women With Pelvic Floor Disorders' on Sept. 28.

Brief Summary: This prospective, non-randomized comparative study evaluated the effects of short-term vaginal treatment with prasterone or estriol in women with pelvic floor disorders who were awaiting urogynecological surgery. A total of 74 women were included, with 37 participants receiving vaginal prasterone and 37 receiving vaginal estriol. Treatment was administered before surgery for approximately 8 weeks. The study assessed changes in pelvic floor symptoms and quality of life using the WHOQOL-BREF questionnaire and symptom severity scales. The...