U.S., Sept. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07797868) titled 'Vacuum-Assisted Closure Versus Graduated Primary Skin Closure for Postoperative Burst Abdomen' on Aug. 27.
Brief Summary: Burst abdomen, or complete abdominal wound dehiscence, is a severe postoperative complication characterized by the separation of the musculo-aponeurotic layer of the abdominal wall. It leads to extended hospital stays, high treatment costs, and an increased risk of long-term incisional hernia. While negative pressure wound therapy using vacuum-assisted closure (VAC) is widely utilized, graduated (staged) primary skin closure remains a common, accessible bedside alternative. Direct randomized comparative evidence ...