U.S., March 21 -- ClinicalTrials.gov registry received information related to the study (NCT07486492) titled 'Using Healthy Gut Bacteria to Boost Immune Treatment for Advanced Bowel Cancer' on March 14.
Brief Summary: This research protocol outlines an exploratory study on the combination of early-life fecal microbiota transplantation (yFMT) with immunotherapy and chemotherapy in patients with microsatellite stable metastatic colorectal cancer (MSS mCRC). The single-center, single-arm study aims to assess the safety of yFMT in conjunction with immunotherapy and chemotherapy, with a secondary focus on exploring its efficacy and impact on the patients' immune microenvironment. The study will enroll 10 patients aged 18-75 who have progressed ...