Clinical Trial: Umbilical Cord Mesenchymal Stem Cell Secretome in Patients With Sjogren's Syndrome

U.S., Nov. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07910526) titled 'Umbilical Cord Mesenchymal Stem Cell Secretome in Patients With Sjogren's Syndrome' on Oct. 26.

Brief Summary: This randomized, placebo-controlled, double-blind trial evaluated the safety and efficacy of umbilical cord mesenchymal stem cell (UC-MSC) secretome, given as an add-on to standard therapy, in women with Sjogren's syndrome. Twenty-nine participants were randomly assigned to receive six intramuscular injections of either UC-MSC secretome or 0.9% sodium chloride (placebo) over five weeks, while continuing their usual corticosteroid and/or immunosuppressant treatment. The main outcome was the change in disease activity measured...