Clinical Trial: Type 2 Inflammation in Adults With Cystic Fibrosis

U.S., Oct. 24 -- ClinicalTrials.gov registry received information related to the study (NCT07892443) titled 'Type 2 Inflammation in Adults With Cystic Fibrosis' on Sept. 22.

Brief Summary: The goal of this observational study is to better understand why some adults with cystic fibrosis (CF) continue to have repeated pulmonary exacerbations, or episodes of worsening respiratory symptoms, despite treatment with highly effective CFTR modulator therapy. The study will focus on whether a type of inflammation called type 2 (T2) inflammation may contribute to these pulmonary exacerbations.

The main questions this study aims to answer are:

Are signs of T2 inflammation more common in adults with CF who have frequent pulmonary exacerbations?

Are ...