Clinical Trial: TRACP-5b for Diagnosis and Follow-up of Giant Cell Tumor of Bone

U.S., May 28 -- ClinicalTrials.gov registry received information related to the study (NCT07609277) titled 'TRACP-5b for Diagnosis and Follow-up of Giant Cell Tumor of Bone' on May 13.

Brief Summary: This prospective observational study will evaluate whether the blood biomarker TRACP-5b can help diagnose and monitor patients with giant cell tumor of bone (GCTB). GCTB is a rare but locally aggressive bone tumor that can return even after surgical treatment. Currently, patients require long-term follow-up based mainly on imaging examinations such as CT or MRI, and suspected recurrence often requires invasive biopsy procedures.

TRACP-5b is an enzyme associated with osteoclast activity that can be measured from a blood sample. Previous studie...