Clinical Trial: Topical Intranasal Anesthetic Block for Reducing the Pain of Botulinum Toxin Injections for Chronic Migraine

U.S., May 7 -- ClinicalTrials.gov registry received information related to the study (NCT07571889) titled 'Topical Intranasal Anesthetic Block for Reducing the Pain of Botulinum Toxin Injections for Chronic Migraine' on Nov. 21, 2025.

Brief Summary: People find the injections used in onabotulinumtoxinA (Botox(R)) uncomfortable. This study will test whether putting a small piece of cotton soaked with 4% lidocaine (a numbing medicine) inside the front of each nostril for 5 minutes before the injections reduces injection pain compared with cotton soaked in saline (salt water).

Study Start Date: March 03

Study Type: INTERVENTIONAL

Condition: Pain From onabotulinumtoxinA Injections

Intervention: PROCEDURE: onabotulinumtoxinA prophylaxis w...