Clinical Trial: Tolerance of Local Administration of Cryopreserved Autologous Stromal Vascular Fraction Combined With Micrograft for the Treatment of Refractory Ano-perineal Fistulas in Crohn's Disease

U.S., June 6 -- ClinicalTrials.gov registry received information related to the study (NCT07629245) titled 'Tolerance of Local Administration of Cryopreserved Autologous Stromal Vascular Fraction Combined With Micrograft for the Treatment of Refractory Ano-perineal Fistulas in Crohn's Disease' on March 31.

Brief Summary: The ADICROHN-3 study is a prospective, multicenter, open-label cohort study.

Its design is supported by the following elements:

* The results of the ADICROHN pilot study (EudraCT No. 2013-002602-31) and our 3-year study, which demonstrate an excellent safety profile with a promising efficacy signal.

* Data from the literature confirming that cryopreservation of FVS does not compromise the clonogenic and differentiation ...