U.S., March 19 -- ClinicalTrials.gov registry received information related to the study (NCT07480317) titled 'TIS for Brain Network Modulation and Clinical Efficacy in Parkinson's Disease' on March 14.

Brief Summary: Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor dysfunction. While deep brain stimulation (DBS) is effective, its invasive nature limits its application in early-stage patients. Temporal interference stimulation (TIS) is a novel non-invasive technique that can target deep brain structures like the globus pallidus internus (GPi) by using high-frequency electric fields.

This study aims to evaluate the clinical value and underlying mechanisms of TIS in PD patients. The research is divided into two...