U.S., Aug. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07776379) titled 'The Prediction of Clinical Outcome Using the Serum BDNF Level' on Aug. 17.
Brief Summary: Low back pain (LBP) is one of the most commonly observed conditions in patients over the age of 50 and imposes a substantial socioeconomic burden. Degenerative disc disease is one of the most frequent and important causes of this pain. Progressive disc degeneration is characterized by a decline in disc cell number and degradation of the extracellular matrix. Loss of nucleus pulposus (NP) volume and hydration, together with fissure formation within the annulus fibrosus (AF), develop gradually with aging and ultimately lead to functional impairme...