U.S., April 15 -- ClinicalTrials.gov registry received information related to the study (NCT07528885) titled 'The GORUN Study: Gradual Onset of RUNning and Knee Joint Health in Novice Runners' on March 28.

Brief Summary: Knee osteoarthritis (OA) is a debilitating disease affecting millions worldwide. Exercise is a core treatment for knee OA, and is advocated by all clinical guidelines. Running is a common exercise that is accessible and evokes a number of positive physical and psychological benefits. However, the appropriateness of recreational running in the presence of knee OA is unclear.

A growing literature base appears to suggest that running may not be deleterious to the health - especially at the knee joint - of people with knee OA...