U.S., Oct. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07888387) titled 'Temporal Interference Stimulation in Major Depressive Disorder: A Pilot Feasibility Study' on Sept. 27.
Brief Summary: This pilot feasibility study used a randomized, double-blind, within-subject crossover design to explore temporal interference (TI) stimulation in adults with major depressive disorder. Fifteen participants received five weekly 20-minute stimulation sessions in randomized order, including TI stimulation targeting the left dorsolateral prefrontal cortex, left subgenual anterior cingulate cortex, right amygdala, and right ventral striatum, as well as a sham stimulation condition. The primary aim was to establish the f...