U.S., March 13 -- ClinicalTrials.gov registry received information related to the study (NCT07468565) titled 'Surgical Approach for the Treatment of Hirschsprung Disease Using the Swenson Technique (SMILES)' on Feb. 11.

Brief Summary: Hirschsprung disease (HD) is a rare congenital disorder of the enteric nervous system, affecting approximately 1 in 5,000 live births. It is characterized by the absence of ganglion cells in the distal colon, leading to functional intestinal obstruction due to impaired peristalsis. Surgical treatment consists of resection of the aganglionic segment-most commonly rectosigmoid-followed by a colo-rectal, colo-anal, or ileo-anal anastomosis.

Among colo-anal pull-through procedures, the Swenson technique was hist...