Clinical Trial: Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients

U.S., June 11 -- ClinicalTrials.gov registry received information related to the study (NCT07639359) titled 'Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients' on June 01.

Brief Summary: **Brief Summary**

Depressive symptoms are frequent among patients admitted to the intensive care unit (ICU) and may be associated with worse clinical outcomes, reduced participation in care, lower treatment adherence, and increased mortality. Conventional antidepressants, including selective serotonin reuptake inhibitors (SSRIs), have limited utility in this setting because of their delayed onset of action, incomplete efficacy, and potential drug interactions in medically complex patients.

Ketamine, an N-methyl-D-as...