Clinical Trial: Spatially Fractionated Radiation Therapy for Locally Advanced Cervical Cancer

U.S., Aug. 25 -- ClinicalTrials.gov registry received information related to the study (NCT07781475) titled 'Spatially Fractionated Radiation Therapy for Locally Advanced Cervical Cancer' on Aug. 19.

Brief Summary: This randomized clinical trial will evaluate whether adding spatially fractionated radiation therapy (SFRT) to definitive chemoradiotherapy improves outcomes in patients with locally advanced cervical cancer. Adult patients with FIGO 2018 stage IIB to IVA cervical cancer who are planned to receive definitive chemoradiotherapy will be randomly assigned in a 1:1 ratio to an SFRT group or a control group.

Both groups will receive external-beam radiation therapy, concurrent chemotherapy, and brachytherapy. Patients with pelvic wall...