Clinical Trial: Short-Chain Fatty Acids in Lypopolysaccharide-Induced Inflammation and Executive Function

U.S., July 21 -- ClinicalTrials.gov registry received information related to the study (NCT07713641) titled 'Short-Chain Fatty Acids in Lypopolysaccharide-Induced Inflammation and Executive Function' on June 30.

Brief Summary: Short-chain fatty acids (SCFAs) are substances produced by gut bacteria when they ferment dietary fiber. They can act as signals between the gut and the brain and may help regulate the body's immune and stress responses. Earlier work has shown that delivering SCFAs to the colon can lower the stress hormone response to a mental stress task in healthy people, and laboratory studies suggest SCFAs can reduce inflammation. However, it is not yet known whether SCFAs can reduce inflammation in humans, or whether doing so pr...