Clinical Trial: Sedation vs No Sedation in Mechanically Ventilated COPD Patients

U.S., June 3 -- ClinicalTrials.gov registry received information related to the study (NCT07620912) titled 'Sedation vs No Sedation in Mechanically Ventilated COPD Patients' on May 13.

Brief Summary: This study aims to evaluate the safety and efficacy of no-sedation compared to daily interruption of sedation (DIS) in mechanically ventilated patients with chronic obstructive pulmonary disease (COPD). Mechanical ventilation is associated with discomfort, anxiety, and agitation, often requiring sedation. However, excessive sedation may worsen outcomes, especially in COPD patients with respiratory failure. This randomized controlled trial will include 100 adult COPD patients admitted to the respiratory ICU and requiring invasive mechanical ven...