Clinical Trial: Sedation Depth and EGJ Endoscopic Grading: A Randomized Controlled Trial

U.S., Oct. 24 -- ClinicalTrials.gov registry received information related to the study (NCT07891455) titled 'Sedation Depth and EGJ Endoscopic Grading: A Randomized Controlled Trial' on Oct. 17.

Brief Summary: Brief Study Summary:

This prospective randomized controlled trial evaluates the impact of procedural sedation depth on the American Foregut Society (AFS) endoscopic grading of esophagogastric junction (EGJ) integrity and its correlation with objective gastroesophageal reflux disease (GERD) severity. A total of 192 adult patients undergoing diagnostic upper endoscopy were randomly allocated across three active sedation arms (Mild, Moderate, and Deep Sedation). Using a dual assessment protocol, AFS grades were recorded before and afte...