U.S., May 7 -- ClinicalTrials.gov registry received information related to the study (NCT07570927) titled 'Salivary Microbiota and Antimicrobial Resistance in Relation to Chlorhexidine Use' on April 30.
Brief Summary: This study evaluated the ecological effects of 0.06% chlorhexidine toothpaste on the salivary microbiota of healthy individuals, focusing on taxonomic composition, functional shifts, and prevalence of predicted antimicrobial resistance genes. Saliva samples were collected from eleven healthy participants at three specific time points: baseline (following a 4-week run-in period using a control toothpaste), intervention (after 12 weeks of using 0.06% chlorhexidine digluconate toothpaste), and washout (after a subsequent 12-week...