U.S., Sept. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07797894) titled 'Safety and Immunogenicity of HPV Vaccine in HIV-infected' on Aug. 27.
Brief Summary: HPV can cause various cancers, including cervical cancer. HIV-infected individuals, due to immune deficiency or long-term immunosuppressive therapy, have significantly higher rates of HPV infection and associated lesion risks compared to the general population. However, clinical research on vaccines for HIV-infected individuals is still in its early stages. This study aims to investigate the safety, immunogenicity, and immune response mechanisms of HPV vaccines in HIV-infected populations. A single-center, prospective, open-label cohort study was co...