Clinical Trial: S1R Imaging-Based Cryoneurolysis in Chronic Pain

U.S., Aug. 18 -- ClinicalTrials.gov registry received information related to the study (NCT07768501) titled 'S1R Imaging-Based Cryoneurolysis in Chronic Pain' on Aug. 12.

Brief Summary: The goal of this clinical trial is to determine whether a sigma-1 receptor PET/MRI scan can help identify the specific nerves responsible for chronic pain.

Researchers will use an investigational imaging agent called [18F]FTC-146 to look for signs of pain generating nerve irritation or injury that may not be visible on convention imaging tests.

Participants whose pain-generating nerve can be identified may undergo a diagnostic nerve block and, if successful, a standard clinical procedure called cryoneurolysis will be used to temporarily interrupt pain sig...