U.S., Sept. 16 -- ClinicalTrials.gov registry received information related to the study (NCT07820501) titled 'Resistance-Optimised Antimicrobial Dosing in Critically Ill Patients, a Randomised Controlled Trial' on Aug. 16.
Brief Summary: Critically ill people who need a breathing machine often develop hospital-acquired lung infections. These infections are commonly treated with the antibiotics piperacillin/tazobactam or meropenem. However, standard antibiotic doses may not always provide the right drug levels to fully treat the infection or help prevent antibiotic resistance.
The purpose of this study is to determine whether a resistance-optimized antibiotic dosing approach improves recovery compared with standard antibiotic dosing in cri...