U.S., March 18 -- ClinicalTrials.gov registry received information related to the study (NCT07476404) titled 'Re-bleeding in Giant Meningioma and Intraoperative Hydroxyethyl Starch (HES) Fluid Therapy' on March 12.
Brief Summary: Project Summary: Retrospective Cohort Study
1. Core ObjectiveThe primary goal is to determine if the volume of Hydroxyethyl Starch (HES) 130/0.4 (specifically Voluven(R) or Volulyte(R)) administered during the removal of giant meningiomas (tumors > 5 cm) increases the risk of postoperative complications.
2. Research Question
Does the volume of intraoperative HES solution influence the rate of re-bleeding (requiring a second surgery within 48 hours) or the development of Acute Kidney Injury (AKI) within 7 days a...