Clinical Trial: Pulse Pressure and Outcomes After Out-of-Hospital Cardiac Arrest

U.S., May 15 -- ClinicalTrials.gov registry received information related to the study (NCT07586878) titled 'Pulse Pressure and Outcomes After Out-of-Hospital Cardiac Arrest' on May 08.

Brief Summary: STEP-PRESS is a predefined exploratory observational substudy nested within the STEPCARE trial. The study will evaluate whether early low pulse-pressure burden after out-of-hospital cardiac arrest is associated with early mortality and selected biomarker outcomes. Pulse pressure will be calculated as systolic blood pressure minus diastolic blood pressure using recorded STEPCARE blood-pressure values. The primary exposure is cumulative hours with pulse pressure below 40 mmHg during the first 12 hours after randomization. The primary outcome is ...