Clinical Trial: Proton Versus Photon Therapy in Head and Neck Squamous Cell Carcinomas.

U.S., May 13 -- ClinicalTrials.gov registry received information related to the study (NCT07580300) titled 'Proton Versus Photon Therapy in Head and Neck Squamous Cell Carcinomas.' on May 06.

Brief Summary: A national, randomized, clinical trial (phase III) investigating radiotherapy with protons compared with photons for patients with squamous cell carcinoma of the head and neck area eligible for radiotherapy, either radical or postoperative, with curative intent. Comparative dose plans with protons and photons will be prepared, and the probability of toxicity evaluated with NTCP models. Patients with presumed benefit from protons will be randomized 1:1 to treatment with protons or photons. The number of randomized participants will be 40...