Clinical Trial: Project E-Shift: A Harm Reduction Intervention for Chronically Unhoused Smokers.

U.S., Oct. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07897058) titled 'Project E-Shift: A Harm Reduction Intervention for Chronically Unhoused Smokers.' on Oct. 09.

Brief Summary: This pilot randomized trial tested whether switching to e-cigarettes, compared with standard nicotine replacement therapy (NRT; patch and gum), helped adults with a history of chronic homelessness stop smoking combustible cigarettes. All participants received brief cessation counseling and incentives for carbon monoxide (CO)-verified abstinence from cigarettes during the first weeks after a scheduled switch date. Participants were followed for 12 weeks after switching, with a final follow-up at 24 weeks. The study also assess...