U.S., June 2 -- ClinicalTrials.gov registry received information related to the study (NCT07617181) titled 'Probiotics Supplementation for Neurodevelopment in Preterm Infants' on May 18.
Brief Summary: The purpose of this randomized controlled trial is to evaluate the effect of daily supplementation with a probiotic mixture on the neurodevelopmental outcomes of preterm infants with a history of neonatal antibiotic exposure. The intervention lasts for 6 months. The study hypothesizes that early gut microbiota remodeling via exogenous probiotics can improve neurodevelopment. The primary outcome is assessed by the Gesell Developmental Schedules or the Ages & Stages Questionnaires (ASQ-3). Secondary outcomes include longitudinal changes in gut...